Supel™ Carbon LC U/HPLC Columns
Porous graphitic carbon (PGC) is a novel stationary phase and gives the chromatographer an additional chemistry option in the separation of challenging, poorly retained polar compounds beyond conventional silica-based reversed-phase chromatography.
The latest addition to the Supelco® HPLC portfolio, the Supel™ Carbon LC, is based on a patented, synthetic process for creating porous graphitic carbon (PGC) particles. This column technology enables scientists to simplify methods for analyzing polar compounds using the familiar reversed-phase approach and without headaches caused by a lack of reproducibility due to method conditions that are more challenging to control.
This new HPLC Column provides distinct application advantages over classical silica:
- Retention of very polar compounds e.g. pesticides and amino acids (without need for HILIC conditions)
- Temperature stability up to 250 °C
- pH stability (1-14)
- Unique retention mechanism
- Compatibility with any solvent
- Unique shape selectivity
Several applications have been developed using this new column technology:
- Analysis of Highly Polar Pesticides
- Analysis of Paraquat and Diquat (Converting an existing HILIC Method to a PGC Method with a simpler gradient
- Separation of Vitamin D2 and D3 Metabolites and their Epimers