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Microspheres & Particles For Diagnostics And Bioprocessing

Polysciences is a world leader in the development of particle-based solutions for diagnostics, bioprocessing and instrument standardization. Our capabilities in life sciences allow us to address the unique requirements of advanced applications in medical devices, biosensors and nanotechnology.

Microspheres & Particles

Polysciences offers the most comprehensive range of particle solutions in the industry. We are your source for organic, inorganic, biodegradable, magnetic, fluorescent, dyed and specific antibody and general protein coated particles in diameters spanning the range of 40 nm to 10 mm.

Standards for Analytical Instruments

Polysciences manufactures a comprehensive range of standards for analytical instruments such as cell analyzers, particle sizers and fluorescence microscopes. Our NIST Traceable Particle Size Standards feature low coefficients of variation, which make these particles suitable for use in a wide range of applications including instrument calibration, particulate testing, filter challenge and clean room testing. Our catalog also includes SureCount™ Particle Count Standards, ViaCheck™ Viability and Concentration Controls, and a broad range of fluorescent and antibody capture beads for flow cytometric and imaging applications.

Magnetic Microspheres & Particles

Our line of BioMag® products include superparamagnetic particles and kits that offer superior performance in the isolation and purification of nucleic acids, antibodies and other proteins. Specific cell populations may be enriched or depleted using our range of BioMag® anti-CD marker particles.

Superparamagnetic particles have been utilized extensively in diagnostic and other research applications for the capture of biomolecules and cells. They confer a number of benefits, including ease of separation and suitability for automation. Magnetic particle-based diagnostic assays demand the highest performance in terms of physical handling, ligand binding characteristics, and signal-to-noise ratios. Bead composition directly impacts settling and magnetic separation profiles, which have implications for assay parameters such as incubation times for binding and elution steps, buffer changes, etc. Most importantly, the composition impacts specific / nonspecific binding characteristics, and background signal arising from the particle itself. These factors have a direct impact on the sensitivity and dynamic range of the assay.

Our comprehensive particle offerings allow us to address the unique requirements of specific assay systems, with options for particle diameter, morphology, surface properties, separation profile, and other characteristics. No other company offers such a complete collection for your screening and development efforts. We synthesize at scales that will carry you from R&D through manufacturing, and under an ISO 13485 Quality System that will meet your regulatory needs. We invite you to explore the vast technical resources on our website, or to contact us directly to discuss your next development project.

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